Detalles de la búsqueda
1.
COVID-19 therapeutics: Challenges and directions for the future.
Proc Natl Acad Sci U S A
; 119(15): e2119893119, 2022 04 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-35385354
2.
Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial.
Lancet
; 401(10373): 281-293, 2023 01 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-36566761
3.
Adaptive multi-interventional trial platform to improve patient care for fibrotic interstitial lung diseases.
Thorax
; 2024 Mar 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-38448221
4.
Adopting human factors in early phase and experimental medicine research: A nested pilot study observing controlled human infection with SARS-CoV-2.
Br J Clin Pharmacol
; 2023 Oct 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-37903635
5.
Inhaled budesonide for COVID-19 in people at high risk of complications in the community in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial.
Lancet
; 398(10303): 843-855, 2021 09 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-34388395
6.
Pharmacodynamic evaluation and safety assessment of treatment with antibodies to serum amyloid P component in patients with cardiac amyloidosis: an open-label Phase 2 study and an adjunctive immuno-PET imaging study.
BMC Cardiovasc Disord
; 22(1): 49, 2022 02 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-35152886
7.
Base of thumb osteoarthritis in UK interface services-a cohort and survey-based study to assess current practice.
Rheumatology (Oxford)
; 60(9): 4094-4102, 2021 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34469568
8.
Effect of ileal bile acid transporter inhibitor GSK2330672 on pruritus in primary biliary cholangitis: a double-blind, randomised, placebo-controlled, crossover, phase 2a study.
Lancet
; 389(10074): 1114-1123, 2017 03 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-28187915
9.
Therapeutic Clearance of Amyloid by Antibodies to Serum Amyloid P Component.
N Engl J Med
; 373(12): 1106-14, 2015 Sep 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-26176329
10.
A randomized, double-blind, placebo-controlled trial of camicinal in Parkinson's disease.
Mov Disord
; 33(2): 329-332, 2018 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29278279
11.
Trials of anti-tumour necrosis factor therapy for COVID-19 are urgently needed.
Lancet
; 395(10234): 1407-1409, 2020 05 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-32278362
12.
BAT117213: Ileal bile acid transporter (IBAT) inhibition as a treatment for pruritus in primary biliary cirrhosis: study protocol for a randomised controlled trial.
BMC Gastroenterol
; 16(1): 71, 2016 Jul 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-27431238
13.
The effect of camicinal (GSK962040), a motilin agonist, on gastric emptying and glucose absorption in feed-intolerant critically ill patients: a randomized, blinded, placebo-controlled, clinical trial.
Crit Care
; 20(1): 232, 2016 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27476581
14.
Current usage of explainer animations in trials: a survey of the UKCRC registered clinical trial units in the UK.
Trials
; 25(1): 224, 2024 Mar 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-38549126
15.
Use of oxygen-loaded nanobubbles to improve tissue oxygenation: Bone-relevant mechanisms of action and effects on osteoclast differentiation.
Biomaterials
; 305: 122448, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38218121
16.
Ivermectin for COVID-19 in adults in the community (PRINCIPLE): An open, randomised, controlled, adaptive platform trial of short- and longer-term outcomes.
J Infect
; 88(4): 106130, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38431155
17.
Cost-utility analysis of molnupiravir plus usual care versus usual care alone as early treatment for community-based adults with COVID-19 and increased risk of adverse outcomes in the UK PANORAMIC trial.
Br J Gen Pract
; 2024 Jan 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-38228357
18.
Randomized controlled trial of molnupiravir SARS-CoV-2 viral and antibody response in at-risk adult outpatients.
Nat Commun
; 15(1): 1652, 2024 Feb 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-38396069
19.
In vivo human keyhole limpet hemocyanin challenge in early phase drug development: A systematic review.
Clin Transl Sci
; 16(3): 357-382, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36420645
20.
Optimising psoriatic arthritis therapy with immunological methods to increase standard evaluation: the protocol of an open-label multicentre, parallel-group, two-arm randomised controlled study evaluation precision medicine approach in the treatment of psoriatic arthritis.
BMJ Open
; 13(9): e078539, 2023 09 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-37770264